During which of the following activities is wearing personal protective equipment (PPE) necessary?

Wearing personal protective equipment (PPE) is essential during the activity of administering injections because it helps prevent the risk of exposure to blood and bodily fluids. PPE, such as gloves and, depending on the situation, masks or goggles, protects both the healthcare professional and the patient from potential infections and contamination.

In contrast, while taking vital signs may involve some risk, it usually does not require the same level of protection as administering injections, where there is a more direct interaction with blood. Assisting with administrative tasks and scheduling appointments does not involve direct patient care or exposure to hazardous materials, making PPE unnecessary in those contexts. Therefore, the requirement for PPE is most evident during procedures that pose a higher risk of exposure, such as injections.